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Fishman, Lila (Ed.)Sex-ratio meiotic drivers are selfish genes or gene complexes that bias the transmission of sex chromosomes resulting in skewed sex ratios. Existing theoretical models have suggested the maintenance of a four-chromosome equilibrium (with driving and standard X and suppressing and susceptible Y) in a cyclic dynamic, but studies of natural populations have failed to capture this pattern. Although there are several plausible explanations for this lack of cycling, interference from autosomal suppressors has not been studied using a theoretical population genetic framework even though autosomal suppressors and Y-linked suppressors coexist in natural populations of some species. In this study, we use a simulation-based approach to investigate the influence of autosomal suppressors on the cycling of sex chromosomes. Our findings demonstrate that the presence of an autosomal suppressor can hinder the invasion of a Y-linked suppressor under some parameter space, thereby impeding the cyclic dynamics, or even the invasion of Y-linked suppression. Even when a Y-linked suppressor invades, the presence of an autosomal suppressor can prevent cycling. Our study demonstrates the potential role of autosomal suppressors in preventing sex chromosome cycling and provides insights into the conditions and consequences of maintaining both Y-linked and autosomal suppressors.more » « less
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We study conversational group detection in varied social scenes using a message-passing Graph Neural Network (GNN) in combination with the Dominant Sets clustering algorithm. Our approach first describes a scene as an interaction graph, where nodes encode individual features and edges encode pairwise relationship data. Then, it uses a GNN to predict pairwise affinity values that represent the likelihood of two people interacting together, and computes non-overlapping group assignments based on these affinities. We evaluate the proposed approach on the Cocktail Party and MatchNMingle datasets. Our results suggest that using GNNs to leverage both individual and relationship features when computing groups is beneficial, especially when more features are available for each individual.more » « less
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